1·Lawlessness is a major problem.
违反法律是一个严重的问题。
—— 《柯林斯英汉双解大词典》
2·Stress is a major problem of modern life.
压力是现代生活中的主要问题。
—— 《牛津词典》
3·One major problem did present itself, though.
不过，确实出现了一个重大问题。
—— 《牛津词典》
4·It would appear that this was a major problem.
看来这是个主要问题。
—— 《牛津词典》
5·Drug abuse has long been a major problem for the authorities there.
毒品滥用长期以来一直是那里的当局的一大难题。
—— 《柯林斯英汉双解大词典》
6·Shopping becomes a major problem, and for anything slightly out of the ordinary you have to go on an expedition to the nearest large town.
购物成了大问题，要想买到任何一种稍不寻常的东西，你就得赶远路到最近的市镇。
7·So this is a major problem.
所以，这是一个大问题。
8·So, it is a problem, major problem.
因此说，这是个问题，是个主要问题。
9·The first major problem is staffing.
第一个主要问题是员工。
10·This is a major problem in the UK.
这就是英国的症结之一。